Researchers from the Diabetes and Obesity Research Institute at the University of Southern California have uncovered concerning evidence regarding the popular sweetener sucralose. Their study indicates that this non-caloric sweetener can increase appetite and promote weight gain. This study provides new insight in the ways short term consumption of sucralose, sucrose and water affects brain activation associated with control of appetite.
The new study employed MRI scans to measure blood flow in the hypothalamus. This region of the brain is absolutely critical for controlling hunger and energy homeostasis. Participants ingested one of three substances—sucralose, sucrose, or water—before having MRI scans performed. By studying the resulting changes in brain blood flow after consumption, researchers hoped to learn how these sweeteners influence feelings of hunger.
In other words, these cumulative findings suggest that sucralose is not as harmless as once believed. The MRI data indicated that people who ingested sucralose had greater blood flow to the hypothalamus. These effects were absent after consuming water or sucrose, in stark contrast to their effect. This corresponding increase in blood flow across the brain indicates that you are likely experiencing greater hunger. Ultimately, this means you might consume more calories, causing an increase in weight.
“After this study, I’m also inclined to recommend my patients minimize non-caloric sweeteners as well.” – Dr. Ali
What the research team at the University of Southern California found might surprise you. Through their meticulous research they uncovered some fascinating new findings on this very cool topic. This study bears key implications. Sucralose can be found in a wide variety of diet products and low-calorie drinks that are sold in stores and advertised as better for you options. These findings call into question the prevailing hypothesis that non-caloric sweeteners may be ingested with no impact on appetite regulation.
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